SKU: 63197017504

5-Amino-1MQ ICCC

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Description

5-Amino-1MQ ICCC5 amino 1MQ What is it? 5 amino 1MQ (5 amino 1 methylquinolinium) is a small molecule inhibitor of the enzyme Nicotinamide N Methyltransferase (NNMT). This enzyme is being extensively studied as a therapeutic target in the battle against chronic diseases associated with obesity and aging. Cellular levels of NNMT increase with aging and in fat cells as they hypertrophy. The enzyme decreases cellular nicotinamide (NMA) by converting it to

5-amino-1MQ

What is it?

5-amino-1MQ (5-amino-1-methylquinolinium) is a small molecule inhibitor of the enzyme Nicotinamide N-Methyltransferase (NNMT). This enzyme is being extensively studied as a therapeutic target in the battle against chronic diseases associated with obesity and aging. Cellular levels of NNMT increase with aging and in fat cells as they hypertrophy. The enzyme decreases cellular nicotinamide (NMA) by converting it to methylnicotinamide (MNA). NMA is the main precursor for synthesis of nicotinamide adenine dinucleotide (NAD), which is critical for energy production in the cell. Reduced levels of cellular NAD+ contribute to the features of aging, including the development of chronic diseases. Furthermore, NNMT uses the methyl donor S-adenosyl methionine (SAM), which is converted in the process to S-adenosyl homocysteine (SAH), and then to homocysteine. The combination of decreased NAD+ and increased homocysteine is a central feature of aging and its associated diseases. NNMT inhibitors like 5-amino-1MQ could go a long way to prevent these changes.

What does it do?

The major use of 5-amino-1MQ at present is for weight loss and to decrease body fat. It can help to remove fat from areas of the body that are normally resistant to fat loss, such as the triceps area and thighs. It alleviates pathologies associated with obesity, including high cholesterol and insulin resistance. It can help to prevent metabolic syndrome or type 2 diabetes, or help to control these conditions. As well as helping with fat loss, 5-amino-1MQ can improve muscle growth and recovery. By increasing cellular NAD+, it can help to increase energy levels and decrease fatigue. It may be useful in patients with chronic fatigue. It has been regarded as an anti-aging compound and may help prevent or diminish the functional decline and chronic disease that occur with aging. It may prevent cancer growth and spread, although, so far, this has only been demonstrated in laboratory studies.

How to use it

5-amino-1MQ is supplied as capsules containing 50 mg of the active ingredient. Up to three capsules can be taken daily. Divide the dose if more than one capsule is used. As it is water-soluble, it should be taken on an empty stomach with a glass of water. If only one capsule is used, it is best taken in the morning before breakfast. It can be used alongside other weight loss or glucose-lowering medications, but only under suitable medical supervision.

Is it safe?

5-amino-1MQ has been extensively studied and no serious side effects have been reported. The side effects that have been reported are non-specific and generally very mild. These include headache, dizziness, difficulty sleeping, nausea, and bloating. It should be used cautiously in those receiving treatment for diabetes as it may interact with glucose-lowering medications and provoke hypoglycaemia. It should not be used if the patient has, or could have, active cancer. Do not prescribe for patients with heart disease or overactive thyroid, unless these conditions are well controlled. 5-amino-1MQ should not be prescribed for women who are pregnant, planning to be pregnant within 3 months, or who are breastfeeding.

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SKU: 63197017504

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4.3 ★★★★★
Based on 5 reviews
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Verified Purchase
Hemet Michael
Belleville, US
★★★★★ 5
Good value.
Color: Dark
Well built, looks good, and the material used are ok.
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Reviewed in the United States on June 4, 2026
I
Verified Purchase
ibuy2much
Fort Morgan, US
★★★★★ 4
Nice office chair!
Color: Dark
This is a nice office chair. All of the features work as stated. I would say the seat is slightly more firm than I prefer, but comfort is subjective. The pleather is soft and I like that the arm rests fold out of the way.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 11, 2026
H
HateToRegister
Fort Morgan, US
★★★★★ 5
This Marsail Executive Office Chair Is Excellent For A Comfortable And Polished Desk Setup
Color: Dark
This Marsail executive office chair is excellent, and it brings together comfort, support and a clean professional look in a very practical way. The PU leather has a smooth, polished presence that suits a desk chair well without looking overly bulky. I appreciate that the design includes flip-up armrests, a height-adjustable seat, swivel movement and rolling mobility in one complete chair. The cushioning gives the chair a substantial seated feel, while the back design adds support without making the chair look heavy. It is an office chair that feels thoughtfully built for daily desk work, focused tasks and general seated comfort. The chair arrived securely protected and in very good condition, with the main parts kept in place well through transit. The PU leather surfaces looked clean, smooth and free from distracting marks when unpacked. The base, wheels, armrests, backrest and hardware all appeared properly finished and ready for assembly. Nothing about the chair parts looked loose, flimsy or poorly handled when it arrived. The included components were organized. The appearance of this chair is one of its strongest qualities because it has a dark, sleek and professional style. The chair fabric gives it a refined executive look, while the breathable mesh center keeps the backrest from appearing too solid or oversized. The flip-up armrests blend into the design nicely and add a cleaner profile when raised. The chair has a balanced shape, with a supportive back, plush seat and wide base that all work together visually. It looks modern without being too flashy, which makes it easy to place with different desks and work areas. Functionality is where this chair becomes especially practical because it is easy to put together and simple to adjust. The height adjustment works well for getting the seat into a comfortable position at a desk. The swivel and rolling movement make it easy to shift, turn and reach without the chair feeling stiff. The reclining range and gentle rocking function add a useful option for leaning back during breaks. The flip-up armrests are especially convenient because they allow the chair to tuck under a desk more easily and create extra freedom of movement when needed. The value is strong because this chair offers several useful features in one well-rounded design. The thicker cushioning, contoured support, PU leather surface, breathable backrest, reclining function and flip-up armrests all add to its usefulness. The sturdy base and stated 300-pound support rating also give it a more dependable feel than a basic desk chair. It provides the comfort expected from an executive chair while still offering space-saving details that make it practical. For the features, comfort and overall build, it delivers a very complete office seating option. I highly recommend this Marsail executive office chair for anyone wanting a comfortable, polished and functional desk chair. It is excellent, easy to put together and built with enough adjustability to support different work habits. The combination of plush cushioning, ergonomic shaping, smooth movement and flip-up armrests makes it especially useful for a home office or workspace. I also like that it has a professional look without sacrificing everyday convenience. It is a strong choice for dependable seating that looks good, works well and offers solid comfort.
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Reviewed in the United States on May 5, 2026
C
Cart Curator
Grantham, US
★★★★★ 5
Comfortable for daily use!
Color: Dark, Color: Dark
After using this chair for work and general desk time, I think it does a nice job balancing comfort, adjustability, and overall build quality without feeling overly bulky or cheap. It feels designed for people who spend long stretches at a desk and want something supportive but still comfortable enough to relax in occasionally. Assembly was straightforward. The instructions were clear, the hardware was organized well, and all the holes lined up properly during setup. I put it together by myself in around 20 minutes without needing extra tools. Once assembled, the chair immediately felt sturdy and stable rather than wobbly. The overall quality is solid for this price range. The PU leather has a soft feel and doesn’t have the stiff plastic-like texture some office chairs use. The stitching looks clean, the armrests feel secure, and the rolling base moves smoothly across the floor. The chair also feels durable overall, especially around the frame and base where cheaper chairs sometimes feel weak or shaky after a few weeks of use. It's very comfortable. The seat cushion is thick and supportive without feeling overly hard, and it stays comfortable during long work sessions. I’ve spent multiple hours at a time sitting in it without constantly adjusting positions or feeling pressure points. The mesh section in the backrest also helps airflow a bit, which keeps it from feeling too hot during extended use. The lumbar support is great. The backrest naturally follows the curve of your spine and provides good lower back support while still feeling relaxed enough for casual sitting. I also liked the higher back design since it supports the upper back and shoulders well during longer periods at the desk. The flip-up armrests ended up being more useful than I expected. They make it easy to slide the chair under the desk when not in use, and they also give more room if you like sitting cross-legged occasionally. Solid chair overally. It has a good mix of comfort, support, ease of use, and practical features without feeling overpriced.
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Reviewed in the United States on May 26, 2026
T
theman
Fort Morgan, US
★★★★★ 4
Comfortable, easy to assemble, but no adjustable armrests
Color: Dark, Color: Dark
The Marsail Executive Office Chair Ergonomic Desk Chair with Flip-up Armrests PU Leather was an easy to assemble chair; I was done within 15 minutes with the included tool. Extra screws were included which was nice as the main pack had broken open and I couldn't find one of the primary screws in the larger box (my guess is I probably tossed it on accident with the packaging material) but had the backup so all was well. The instructions were well written and clear. I've now had the chair in my office for over a week. For context; I work from home and also am a PC gamer so I spend a sizeable portion of my time at my desk in the chair. I also live in the southeast US and its April when I am writing this review. With that said; its been in the 70s/80s regularly so feel like I can comment fairly on its performance in warmer temps; though I'll have to try and remember to comeback and update it for the summer season when AC is on full blast and humidity is higher (and the inevitable "swamp butt" sets in). In the first week I've found the chair to be comfortable to sit in. It is wide enough and the arm rests to the side enough that I can sort of lean left and right without much trouble. I like this wider seat and armrests compared to chairs with more narrow span as I tend to shift and move a lot while sitting. The PU leather material feels nice against my clothes and does "grip" the clothing which helps with my tendency to want to slide forward when sitting. At first I thought the "grip" would be annoying but I sort of like it after a week of using the chair. The cushion material is comfortable for sitting and rebounds well after I've been sitting in it for a long period of time. The armrests feature the same sort of cushion and PU leather material which makes them comfortable to sit back and lean on. For the price I think this is a solid office chair and a comfortable option. Longevity will only be tested over time so I'll see if I can remember to update this review over time. I am happy with the chair in my office. A few downsides about the chair that I have: - The wheels are very stiff and don't roll as smoothly as I'd like. They stay put when I am sitting at the desk but when I need to push away they take a bit of force. - The arm rests can't be adjusted for height. They are one height and can only be moved out of the way completely. For someone like who likes to lean or shift sides this is less than ideal as I'd normally make adjustments to the armrests. With that said it is nice to be able to move them out of the way completely when I don't need them. - Lumbar support could be better. I will be using additional support in the chair for my back.
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Reviewed in the United States on April 13, 2026

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