SKU: 6591556221

Natural Factors Acetyl-L-Carnitine 500mg - 60 Capsules

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Description

Natural Factors Acetyl-L-Carnitine 500mg - 60 CapsulesProduct Information Carnitine and its derivatives exist in a carnitine pool in the body. Cellular enzymes and transporters rapidly convert the carnitine to the required form and transport it to the tissues. Carnitine and its derivatives play a key role in fat, carbohydrate, and protein metabolism and energy production and are critical components for mitochondrial metabolism. Acetyl L carnitine (ALC) is the most important derivative of carnitine and

Product Information

Carnitine and its derivatives exist in a carnitine “pool” in the body. Cellular enzymes and transporters rapidly convert the carnitine to the required form and transport it to the tissues. Carnitine and its derivatives play a key role in fat, carbohydrate, and protein metabolism and energy production and are critical components for mitochondrial metabolism. Acetyl-L-carnitine (ALC) is the most important derivative of carnitine and occurs naturally in the body. Because ALC is considered to have greater bioavailability and is therefore more able to cross neurological membranes, it is the preferred form to take for promoting neurological health. 

The levels of carnitine and its derivatives are critical to normal biological functioning. Carnitine is present in the diet in red meats and dairy products, and humans can make carnitine from the amino acids lysine and methionine. However, carnitine deficiency can occur with metabolic disorders, and in conditions such as diabetic neuropathy (nerve pain) and other complications of diabetes. 

ALC has been studied in various conditions including neurological and cognitive disorders such as Alzheimer’s, dementia, depression, neuropathies, and cardiovascular disease, as well as with respect to the fatigue and pain associated with conditions such as chronic fatigue syndrome and sciatica.

Main selling features

  • The most important derivative of carnitine, and the preferred form to take, as it is the most bioavailable
  • Able to cross the blood-brain barrier
  • Has many neurological benefits, including cognitive ability, memory, and mood
  • Naturally occurring nutrient, free from toxic effects

How it works

Acetyl-L-carnitine is the most abundant naturally occurring derivative of carnitine. ALC helps the body produce energy at the cellular level; regulates carbohydrate, lipid and protein metabolism; facilitates fatty acid entry into the mitochondria; and maintains the homeostasis of coenzyme A. ALC also displays potent antioxidant effects and supports repair mechanisms. ALC has been shown to support heart and brain function, muscle movement, and numerous other body processes. 

ALC protects and enhances the activity of neurons and transmitters in the mitochondria and reduces oxidative stress. By improving cellular function and effi ciency in the mitochondria, ALC stabilizes the fl uidity and function of cell membranes, and improves energy production. ALC is involved in peripheral nerve regeneration and has shown promise in improving neuropathy. Because ALC is able to cross the blood-brain barrier it is able to exert its neuroprotective effects in the brain. Studies have shown ALC can improve cognitive performance and mood by protecting against oxidative stress and reducing or blocking the neuronal death that occurs with dementia and other neurodegenerative conditions. 

Supplementation with ALC may be useful in a broad range of conditions, including Alzheimer’s, dementia, age-related memory loss and depression, fatigue, diabetic neuropathy, and cardiovascular disease.

Positioning Line

Boosts physical and mental energy

Ingredients
Each Capsule Contains:  
Acetyl-L-Carnitine 
(N-Acetyl L-carnitine hydrochloride)
500 mg

Non-Medicinal ingredients

Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), silica.  

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SKU: 6591556221

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Ct
Houston, US
★★★★★ 4
Good. I like
Size: 8, Color: Black/White, Size: 8, Color: Black/White
Seem good. Comfortable. True size
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Reviewed in the United States on March 21, 2026
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Turtlespit
Port Orchard, US
★★★★★ 2
Poor sole design could result in injury to heel.
Size: 11, Color: Grill/Mint Wave
These would be so much better if the sole did not expose the heel to possible punctures. There is an actual cutout of the sole where only the spongy part of the shoe is exposed to the heel. Anything sharp will go right through.
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Reviewed in the United States on November 25, 2025
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tom chang
Bozeman, US
★★★★★ 5
Good comfort, quality and classy
Size: 8.5, Color: Black/Ivory
’ve been wearing Cole Haan dress sneakers for work and travel, and they strike a really good balance between professional and comfortable. The biggest advantage is how lightweight they feel compared to traditional dress shoes. Most styles have sneaker-like cushioning, so you can walk or stand all day without your feet getting destroyed. The design is also versatile and look polished enough for business casual outfits but still casual enough to wear with jeans. They work especially well in office environments where a full formal shoe feels too stiff or outdated.
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Reviewed in the United States on May 10, 2026
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Daniel C
Grantham, US
★★★★★ 5
New Favorite Work Shoe
Size: 9.5, Color: Black/Ivory
These Cole Haan Grand Crosscourt Daily shoes have quickly become my new favorite work shoes. They’re incredibly comfortable right out of the box, with just the right amount of cushioning and support to get through long days on my feet. I love that they look sleek and professional while still feeling casual enough to wear anywhere. The build quality is top-notch—durable materials and solid construction that make them feel like they’ll last a long time. Overall, these shoes strike the perfect balance between comfort, style, and practicality. I can honestly say I look forward to wearing them every day. Highly recommend for anyone who spends a lot of time on their feet but doesn’t want to sacrifice style.
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Reviewed in the United States on February 9, 2026
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Edward Diaz
West Palm Beach, US
★★★★★ 5
Well Made for price and style
Size: 10.5, Color: Black/Ivory
Great fit and very flexible. I also recommend buying shoe savers when purchasing this product. To help with toes wrinkles. The pair itself is stylish and very comfortable. Any purchase of this product will be greatly satisfied.
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Reviewed in the United States on April 16, 2026

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