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Description
PE Mouse Anti-Human CD34 Antibody (4H11)Product Specification Host Mouse Antigen CD34 Synonyms Hematopoietic progenitor cell antigen CD34 Location Cell membrane Accession P28906 Clone Number 4H11 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample human PBMC Purification Protein G Conjugation PE Physical Appearance Liquid Storage Buffer PBS, 0. 1% BSA, 0. 2% Proclin 300 Stability & Storage 12 months from date of receipt reconstitution, 2 to 8 C as supplied
Product Specification
| Host | Mouse |
| Antigen | CD34 |
| Synonyms | Hematopoietic progenitor cell antigen CD34 |
| Location | Cell membrane |
| Accession | P28906 |
| Clone Number | 4H11 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | human PBMC |
| Purification | Protein G |
| Conjugation | PE |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 0.1% BSA, 0.2% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 10μl per million cells in 100μl volume | Hu |
Background
CD34 is a transmembrane phosphoglycoprotein protein encoded by the CD34 gene. CD34 derives its name from the cluster of differentiation protocol that identifies cell surface antigens. CD34 was first described on hematopoietic stem cells independently by Civin et al. and Tindle et al, as a cell surface glycoprotein and functions as a cell-cell adhesion factor. It may also mediate the attachment of hematopoietic stem cells to bone marrow extracellular matrix or directly to stromal cells. Clinically, it is associated with the selection and enrichment of hematopoietic stem cells for bone marrow transplants. Due to these historical and clinical associations, CD34 expression is almost ubiquitously related to hematopoietic cells.
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