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Description
CD35 Recombinant Rabbit mAb (SDT-R224)Product Specification Host Rabbit Antigen CD35 Synonyms Complement receptor type 1, C3b C4b receptor, erythrocyte complement receptor 1 (CR1) Location Membrane Accession P17927 Clone Number SDT R224 Antibody Type Recombinant mAb Application WB, IHC P Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage 12
Product Specification
| Host | Rabbit |
| Antigen | CD35 |
| Synonyms | Complement receptor type 1, C3b/C4b receptor, erythrocyte complement receptor 1 (CR1) |
| Location | Membrane |
| Accession | P17927 |
| Clone Number | SDT-R224 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| IHC | 1:500 | null |
Background
CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, follicular dendritic cells and renal foot cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. In pathology, it is mainly used in the diagnosis of follicular dendritic cell tumor.
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