SKU: 33241568813

Mouse Anti-Human CXCR6 Antibody (S-3884)

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Description

Mouse Anti-Human CXCR6 Antibody (S-3884)Product Specification Host Mouse Antigen CXCR6 Synonyms C X C chemokine receptor type 6; CXC R6; CXCR 6; CDw186; G protein coupled receptor STRL33; G protein coupled receptor bonzo; CD186; BONZO; STRL33; TYMSTR Location Cell membrane Accession O00574 Clone Number S 3884 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein A Concentration 2 mg ml Conjugation Unconjugated Physical

Product Specification


Host Mouse
Antigen CXCR6
Synonyms C-X-C chemokine receptor type 6; CXC-R6; CXCR-6; CDw186; G-protein coupled receptor STRL33; G-protein coupled receptor bonzo; CD186; BONZO; STRL33; TYMSTR
Location Cell membrane
Accession O00574
Clone Number S-3884
Antibody Type Mouse mAb
Isotype IgG2a,k
Application FCM
Reactivity Hu
Positive Sample Human PBMC
Purification Protein A
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1:200 Hu

Background

CXCR6 (C-X-C motif chemokine receptor 6), also known as STRL33 and T-lymphocyte-expressed seven-transmembrane domain receptor (TYMSTR), is a G protein-coupled receptor (GPCR) that specifically binds to its unique ligand CXCL16, a transmembrane chemokine that can also be cleaved to function as a soluble chemokine. CXCR6 is predominantly expressed on memory/effector T cells, natural killer T (NKT) cells, natural killer (NK) cells, and plasma cells, playing critical roles in immune cell trafficking, adhesion, and activation. The CXCR6-CXCL16 axis is essential for the recruitment and positioning of immune cells in various tissues, particularly in the liver, spleen, and inflamed sites, and has been implicated in numerous pathological conditions including chronic inflammation, autoimmune diseases, infectious diseases, and cancer. In oncology, CXCR6 expression on tumor-infiltrating lymphocytes (TILs) is associated with improved prognosis in certain cancers, while its expression on tumor cells can promote metastasis and disease progression. The receptor signals primarily through Gαi proteins, activating downstream pathways such as PI3K/AKT, MAPK/ERK, and calcium mobilization, thereby regulating cell migration, survival, and proliferation. Given its selective expression on activated immune cells and its involvement in disease pathogenesis, CXCR6 represents an attractive therapeutic target for immunomodulatory strategies and precision medicine approaches.

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SKU: 33241568813

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4.8 ★★★★★
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Product Reviews
J
J. Lam
Whiting, US
★★★★★ 4
most can fit saros 10, but not all
Color: Saros 10R/Qrevo CurvX Accessories Kit, Color: Saros 10R/Qrevo CurvX Accessories Kit
I should have done a little more research with these. I purchased this for a Saros 10, i thought the Saros 10 and 10R was basically the same besides the filters. I was wrong. Although the brushes are the same size, they didnt fit. They lacked a special metal piece on one side, and the 10R has a different shape on the other, cant even jerry rig it to fit. The filters didnt fit my Saros 10, but that didnt cause the dropped rating, but they quality of it looks very good, and seems well made. The side brushes are good and they fit my Saros 10, replaced them and didnt have a problem. The bags also fit and they are very good. The mopping brushes did not fit, but it was very well made and definitely wasnt just a cheap set. The brush and screw driver were just to add additional number counts and basically useless.
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Reviewed in the United States on January 26, 2026
A
Verified Purchase
Amazon Customer
Natrona Heights, US
★★★★★ 5
Works great
Size: normal
Works great
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Reviewed in the United States on February 14, 2026
A
Verified Purchase
Angie K
Massapequa, US
★★★★★ 5
Get the OEM mop cloths
Size: normal
When buying accessories for my eufy robot vac, I originally got my hands on some dupe accessories because they were cheaper. However- the mop cloths did not work well. The cheap construction of the dupes caused threads to constantly come out and get tangled, causing the robot to error out. I got these OEM ones and they work MUCH better. In this case it's best to buy the OEM parts even though they are more expensive!
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Reviewed in the United States on December 29, 2025
A
Verified Purchase
A R
San Leandro, US
★★★★★ 5
Perfect
Size: normal
Needed more sets because I like to wash the pad after each use. Quality is very good.
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Reviewed in the United States on April 4, 2026
C
Verified Purchase
Computerben
Draper, US
★★★★★ 5
Practical and Effective Mop Cloths!
Size: normal
The Eufy Accessory Washable Vacuum Mop Cloths are a must-have for anyone using the X10 Pro Omni. They are durable, easy to clean, and do an excellent job of tackling dirt and spills on hard floors. Being washable makes them eco-friendly and budget-friendly too! These cloths enhance the efficiency of the vacuum-mop system, making floor cleaning effortless and thorough. Highly recommended for maintaining spotless floors!
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Reviewed in the United States on April 15, 2025

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