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Description
Histone H3 (tri methyl K27) Recombinant Rabbit mAb (SDT-431-118)Product Specification Host Rabbit Antigen H3K27me3 Synonyms Histone H3 (tri methyl K27),H3K27me3 Immunogen Synthetic Peptide Location Nucleus Accession P68431 Clone Number SDT 431 118 Antibody Type Recombinant mAb Application WB, IHC P, ICC, ICFCM, IP Reactivity Hu, Ms, Rt Predicted Reactivity SeUr, Fu, Hm, Pl, Dr Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0.
Product Specification
| Host | Rabbit |
| Antigen | H3K27me3 |
| Synonyms | Histone H3 (tri methyl K27),H3K27me3 |
| Immunogen | Synthetic Peptide |
| Location | Nucleus |
| Accession | P68431 |
| Clone Number | SDT-431-118 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, ICC, ICFCM, IP |
| Reactivity | Hu, Ms, Rt |
| Predicted Reactivity | SeUr, Fu, Hm, Pl, Dr |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IP | 1:50 | |
| IHC | 1:500 | |
| ICC | 1:500 | |
| ICFCM | 1:500 | |
| Dot bolt | 1:1000 |
Background
H3K27me3 is an important type of transliteration inhibitory translation modification. It mainly exists in the promoter of gene -dense areas and plays a role in all aspects of the biological process with the development regulatory factors in the embryo stem cells. H3K27me3 is lacking in the expression of about 50% malignant peripheral nerve sheath tumor (MPNST), and the nerve sheath tumor is positive. In pathology, it is mainly used in the differentiated diagnosis of malignant peripheral nerve sheath tumors, especially high level malignant peripheral nerve sheath tumors (lack of expression) and similar tumors.
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