SKU: 48075869372

Galectin-3 Recombinant Rabbit mAb (SDT-370-78)

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Description

Galectin-3 Recombinant Rabbit mAb (SDT-370-78)Product Specification Host Rabbit Antigen Galectin 3 Synonyms Gal 3, Mac 2 antigen, IgE binding protein, Lectin L 29, CBP 35, L 31 Immunogen Recombinant Protein Accession P17931 Clone Number SDT 370 78 Antibody Type Recombinant mAb Application Sandwich ELISA Reactivity Hu Cross Reactivity Does not recognize galectin 9 Purification Protein A Concentration 2 mg ml Purity >95% by HPLC Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS

Product Specification


Host Rabbit
Antigen Galectin-3
Synonyms Gal-3, Mac-2 antigen, IgE-binding protein, Lectin L-29, CBP 35, L-31
Immunogen Recombinant Protein
Accession P17931
Clone Number SDT-370-78
Antibody Type Recombinant mAb
Application Sandwich ELISA
Reactivity Hu
Cross Reactivity Does not recognize galectin-9
Purification Protein A
Concentration 2 mg/ml
Purity >95% by HPLC
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer PBS pH7.4, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
Sandwich ELISA N/A

Background

Human galectin-3 is a 35 kDa protein that is coded by a single gene, LGALS3, located on chromosome 14. The N-terminal domain of galectin-3 is essential for its multimerization, sensitive to proteolysis by matrix metalloproteinases and may participate in the interaction with other intracellular proteins. Furthermore, the first 12 amino acids of galectin-3 are necessary for its secretion and nuclear translocation. The C-terminal CRD of galectin is responsible for its interaction with glycoconjugates containing N-acetyllactosamine. Thus, galectin-3 binds proteins in a carbohydrate-dependent and -independent manner. Galectin-3 is pivotal in numerous biological activities including cell growth, apoptosis, pre-mRNA splicing, differentiation, transformation, angiogenesis, inflammation, fibrosis and host defense. Both increased and decreased expression levels of galectin-3 are observed in various types of disease including heart, renal and liver disease, cancer and infections. Its prognostic value in predicting the outcomes of Heart failure (HF) and its diagnostic value in thyroid carcinoma diagnosis have been extensively investigated, and indicate its potential application for HF prognosis and thyroid carcinoma diagnosis.

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SKU: 48075869372

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4.7 ★★★★★
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Product Reviews
K
Verified Purchase
Kimberly G
Fort Morgan, US
★★★★★ 5
delightful read
Format: Kindle
What a delightful read. The characters are awesome, the plot was so good, I loved it. I was intrigued and it kept me wanting more. Told in multiple pov, the book sucks you in and doesn’t let go. I cannot wait to read the next book.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 30, 2025
K
Verified Purchase
Kimberly B
Massapequa, US
★★★★★ 4
not bad
Format: Kindle
I loved the plot of this book. The characters just didn’t have a lot of depth. The connections and “love” just weren’t communicated very well in the writing. The author didn’t write the sweet psycho trope very well at all either. Lachlan was just a mess of a character.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on November 17, 2023
C
Verified Purchase
Carmen Alicea
Lake Worth, US
★★★★★ 5
A Beta Worth Rooting For
Format: Kindle
In Spare, Violet Fox flips the omegaverse on its head, giving us a Beta heroine determined to make her mark. Joining the Beta Trials to support her sick father, she's thrown into a pack that doesn't want her, especially the possessive Alphas. But here's the twist: their sweet Omega turns out to be her scent match. Cue the angst, forbidden tension, and a slow-burn romance that will make your heart ache in the best way. Violet Fox delivers an emotional, refreshing take on the genre, proving Betas aren't "spares." They're stars.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 10, 2025
C
Verified Purchase
C. Hunter
Pawtucket, US
★★★★★ 5
Beta, Alpha, Omega oh my!
Format: Kindle
Omegas are precious and given to Alphas & their packs... but the Betas want in too. To this end, the Beta government is rolling out its trial of assigning a Beta to each Alpha-Omega pack. But forcing a Beta into a pack where they are not wanted will not end well... Of course, no one expected the Omega to fall for the assigned Beta. Great read and cliffhanger
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 15, 2025
B
Verified Purchase
B. Stubby
Louisville, US
★★★★★ 3
A familiar story, just with…..less.
Format: Kindle
So, as other reviewers make clear, this is very similar to Pack Darling and The Beta. It’s much closer aligned with The Beta, in plot and maybe more like Pack Darling with characters. That being said, I don’t hate this…..but it wasn’t great either. It’s both books mentioned but just….less. Less angst, less emotion, less feeling. The plot feels very half fleshed out, and the “bad guy” feels underwhelming. I didn’t really feel any real emotions from and of the male leads, except maybe Oliver. The others fell sorta flat for me. And Mika makes herself out to be this big bad ass straight outta training and then we never see it from here again with the one fitting room incident as the exception. SPOILER: The whole, “Oh, I’m actually probably an Omega, but I don’t wanna be but I do actually wanna be but no one can ever know my secret that I do nothing to hide “ thing fell so flat. She never commutes to believing she was secretly an omega, but also mentions her “secret” a lot. It just felt so manufactured. I’m intrigued enough to read part 2 and see how the author closes everything out, but this is not one I’ll recommend or ever come back to.
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Reviewed in the United States on February 13, 2024

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