SKU: 50423812708

Human IL-12/IL-23 p40 ELISA Kit

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Description

Human IL-12/IL-23 p40 ELISA KitProduct Specification Species Reactivity Human Synonym Human IL 12 ELISA kit, IL 23 p19 IL 12 p40, IL23, IL 23, IL 23A, IL 23 A, IL 23p19, IL 23p19 IL 12p40, IL23P19P19, interleukin 23 p19 subunit, interleukin 23, alpha subunit p19, interleukin 23 subunit alpha, Interleukin 23 subunit p19, JKA3 induced upon T cell activation, MGC79388, SGRF, SGRFIL 23 subunit alpha, Description Detection principle: Double antibody sandwich ELISA was used in this

Product Specification

Species Reactivity Human
Synonym Human IL-12 ELISA kit, IL-23 p19/IL-12 p40, IL23, IL-23, IL-23A, IL-23-A, IL-23p19, IL-23p19/IL-12p40, IL23P19P19, interleukin 23 p19 subunit, interleukin 23, alpha subunit p19, interleukin-23 subunit alpha, Interleukin-23 subunit p19, JKA3 induced upon T-cell activation, MGC79388, SGRF, SGRFIL-23 subunit alpha,
Description

Detection principle:

Double antibody sandwich ELISA was used in this experiment. Anti-human IL-12/IL-23p40 monoclonal antibody is coated on a microplate, and IL-12/IL-23p40 in samples and standards will bind to the antibody immobilized on the plate, and the free components will be washed away; Horseradish peroxidase-labeled anti-human IL-12/IL-23 p40 polyantibody was added and unbound antibody was washed away; Adding a substrate solution (chromogenic agent), the color of the solution is proportional to the bound target protein; A stop solution was added to stop the reaction, and the absorbance value was measured at a wavelength of 450 nm (reference calibration wavelength of 540 nm or 570 nm).

Test Type:Double antibody sandwich method

Form:Pre-coated 96-well plate

Test Sample Type:Cell supernatant, serum, plasma

Sample Load:100ul

Kit Components:

A copy of the pre-coated 96-well plate, standard, anti-human IL-12/IL-23 p40 detection antibody, buffer for dilution, chromogenic solution (A, B), wash solution, stop solution, SA-HRP, plate sealing membrane, and instructions.

Sensitivity:3.5 pg/mL

Detection range:62.5-4,000 pg/mL

Recovery Range:89-114%

Save Method:2-8℃

Standard curve plot

Background:

IL-12, also known as natural killer cell stimulating factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a pleiotropic cytokine mainly produced by antigen-presenting cells (monocytes/macrophages, dendritic cells, and B lymphocytes). IL-12 has a variety of effects on T lymphocytes and natural killer (NK) cells, including the ability to stimulate cytotoxicity, proliferation, cytokine production, and Th1 subset development.

IL-12 is a 70 kDa (p70) heterodimeric glycoprotein linked by disulfide bonds, consisting of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. The p40 and p35 subbases do not possess IL-12 activity in themselves, but homodimers of p40 have been shown to bind IL-12 receptors and are IL-12 antagonists.

The genes of human p40 and p35 located on chromosomes 5 and 3, respectively, are independently regulated. The expression of p35 mRNA has been found to be almost ubiquitous, however, the p35 subunit was not detected in the culture supernatant of cells expressing p35 or p35 and p40 mRNA only. The p40 mRNA expression level was higher in cells expressing both p35 and p40 mRNA, and together with the heterodimeric IL-12 p70, a free p40 subunit unrelated to the p35 subunit was secreted. Most of the free p40 subunits secreted by the various human cell lines examined have been found to exist in monomeric form. The content of free p40 far exceeds p70 in the supernatants of various activated human monocytes, and the levels of p70 measured by bioassays are consistent with those measured using p70-specific immunoassays, suggesting that p40 monomers are not potent IL-12 antagonists. Currently, the physiological role of the free p40 subunit is unclear.

 

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SKU: 50423812708

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Mom who does everything
Battle Creek, US
★★★★★ 5
My Favorite Mask
Scent: Collagen, Size: 4 Count (Pack of 1)
I’ve been really impressed with this Bio-Collagen hydrogel mask! It feels incredibly cooling and soothing on the skin, especially after a long day. The overnight wear is a huge plus—you wake up with your skin feeling noticeably more hydrated, plump, and smooth. It doesn’t feel heavy or sticky, and it stays in place better than most sheet masks. After a few uses, I’ve noticed my skin looks more refreshed and even, and my pores appear a bit more minimized. It’s a great option when your skin needs a little extra boost or before an event when you want that “glow.”
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Reviewed in the United States on May 5, 2026
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Ashley
Omaha, US
★★★★★ 4
Woke Up Glowing ✨ (But Sleeping In It Is a Stretch lol)
Scent: Collagen, Size: 4 Count (Pack of 1)
I was honestly impressed with this mask! It feels super soft, cooling, and refreshing while wearing it. The jelly texture makes it feel really hydrating and luxe, like a mini spa night at home. My skin looked smooth, plump, and GLOWING the entire next day after I took it off. Like… noticeably radiant. I also have sensitive skin, so I was a little nervous trying it at first, but I didn’t have any irritation or reaction at all. My skin felt calm, hydrated, and refreshed afterward. One thing I actually liked was that the mask was easy to customize a little. I have a nose piercing, so I just tore a small piece near my nose so it would fit comfortably without irritating it. The material held up perfectly, so that was a nice bonus for anyone with piercings or who just needs a better fit in certain areas. My only complaint is the “sleep in it” part of the instructions. I personally don’t see how that’s possible 😅 The mask stays pretty moist and jelly-like the whole time, so it felt uncomfortable to lay down in and I kept feeling like it would slide around. I ended up just wearing it for a while before bed instead. Overall though, the results were worth it and I’d definitely use it again for the glow alone!
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Reviewed in the United States on May 3, 2026
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Amy Marie Anderson
Birmingham, US
★★★★★ 5
Absolutely amazing masks!!!
Scent: Collagen, Size: 4 Count (Pack of 1)
These masks are beyond amazing! I use one once a week and leave it on overnight after completing my p.m. skincare routine and wake up to smooth, plump, moisturized, and absolutely glowing!! I have extremely sensitive skin and eyes and these masks do not bother me at all. No burning in my eyes and no irritation of the skin. My deep wrinkles seem a lot less pronounced and some of my more fine lines almost disappear for 24 hours after using this mask. They are simple to use and adhere to the skin perfectly even after applying serums and moisturizers. Once the mask is completely absorbed and becomes clear it peels of the skin with ease. Based on the quality of these masks I am shocked by the low price, it is such a great value for your money. This Mask has become a staple in my skincare routine and I will continue to purchase these!!
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Reviewed in the United States on May 10, 2026
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Tara Rekatsinas
Draper, US
★★★★★ 5
instantly more hydrated + glowy skin
Scent: Collagen, Size: 4 Count (Pack of 1), Scent: Collagen, Size: 4 Count (Pack of 1)
I love this mask. It’s one of those products you can actually see a difference with right after using it. It really helps with: 1. Deep hydration – my skin feels plump and moisturized, not dry or tight 2. Smoother texture – it softens everything and makes my skin feel really smooth 3. Glow/brightness – gives that fresh, healthy glow without looking greasy How I use it: I apply it on clean skin (usually at night), leave it on as directed, and let it fully absorb before removing. I like using it when my skin feels dull or dry and want a quick reset. Overall, it’s super easy to use and makes my skin look more refreshed every time. Definitely a go-to for me.
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Reviewed in the United States on April 28, 2026
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Firethorn
San Leandro, US
★★★★★ 5
Love ❤️ this product! 100% recommend!
Scent: Collagen, Size: 16 Count (Pack of 1)
My initial encounter with these was until TikTok but I ordered them from Amazon for myself and my daughter for convenience and Prime shipping. There were two choices I think the one is a four-pack and the one I got is a 16 pack. The 16 pack will last you 4 months if you're doing it once a week as instructed. I open the top and two sides when I'm doing it just to have accessibility and to be able to use the remnants liquid in the pack after I'm done applying the facial part I put the liquid in the pack on my neck and chest. They are a little slippery when you take them out. I watched a video on how to apply it and did the bottom part first and then the top part sometimes I have to snip the top part near the nose to get it to fit properly but you don't have to in general. There are three pieces that are left over the two eye pieces and the lip piece. You can put them below your eyes or above your eyes on your brows and then put the mask over them which is what I do. Or you can put them under your eyes and put the mask over them but I find it doesn't absorb all the way in that location due to the double thickness I guess. The lip one you can put over your lip or put it on vertically over your throat where the skin can get a little saggy. Once you have it on it's best to sit back and relax for 30 minutes or so at about a 45° angle so it doesn't slip off. After about 10 to 15 minutes it doesn't slip around as much and after 30 it's obviously started absorbing and tends to stay pretty well. I haven't noticed any staining on the pillows or anything like that from it and by morning actually by 4 hours later it's completely absorbed and all you have left on your faces the plastic that it was attached to. You just pull that off and throw it away. It's white when you put it on and it's clear when it absorbs. I definitely noticed an improvement in my skin quality and the collagen sinks in easily and less about a week. I am a redhead with delicate skin and I haven't had any reaction to this product at all I know that other masks have caused problems for friends but I've used this one for over a year now and I love it. My daughter and I both use it weekly and they're easy to take with you if you're traveling great way to pamper your skin after a day outside on the beach. The price is reasonable for what it is and what it does. I've gotten several compliments on my skin and I'm over 60 so that saying something for the results! All in all this is a very good product, it doesn't smell and doesn't seem to have any impurities like some others. My skin isn't irritated by it and looks great afterwards. If you're wondering if it washes off once it's soaked in you can wash your face all you want but you're just going to have beautiful glowing cheeks. I wouldn't hesitate to recommend this or give it as a gift!
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Reviewed in the United States on June 11, 2025

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