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Description
IL-18Rα/IL-1R5 His Tag Protein, HumanProduct Specification Species Human Synonyms CD218a, CD218a, CDw218a, IL18R1, IL18RA, IL 18Ralpha, IL 18R alpha, IL18Ralpha2, IL1RRP, IL 1Rrp, Interleukin 18 receptor 1, IL 1 R5, IL 1 Rrp, IL 18 R alpha, IL 18 R1, IL18R alpha, IL18R1, IL 18Ra Accession Q13478 Amino Acid Sequence Cys22 Arg329, with C terminal His Expression System HEK293 Molecular Weight 53 72kDa (Reducing) Purity 95% by SDS PAGE &95% by SEC HPLC Endotoxin <0. 1EU g Conjugation
Product Specification
| Species | Human |
| Synonyms | CD218a, CD218a, CDw218a, IL18R1, IL18RA, IL-18Ralpha, IL-18R-alpha, IL18Ralpha2, IL1RRP, IL-1Rrp, Interleukin-18 receptor 1, IL-1 R5, IL-1 Rrp, IL-18 R alpha, IL-18 R1, IL18R alpha, IL18R1, IL-18Ra |
| Accession | Q13478 |
| Amino Acid Sequence | Cys22-Arg329, with C-terminal His |
| Expression System | HEK293 |
| Molecular Weight | 53-72kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE &＞95% by SEC-HPLC |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, 5% trehalose, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1.Parnet, P. et al. (1996) J. Biol. Chem. 271:3967. |
Background
Interleukin 18 (IL-18) is a member of the IL-1 family of cytokines and shares numerous immuno-regulatory functions with IL-12. The functional IL-18 receptor complex is composed of two subunits designated IL-18 R alpha (also termed IL-1 R5 and IL-1 Rrp) and IL-18 R beta (also termed IL-1 R7 and AcPL). Both IL-18 R alpha and IL-18 R beta belong to the IL-1 receptor superfamily. IL-18 R is widely expressed in numerous tissues including spleen, thymus, leukocyte, liver, lung, heart, small and large intestine, prostate and placenta. Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells. Contributes to IL18-induced cytokine production, either. independently of SLC12A3, or as a complex with SLC12A3.
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4.6 ★★★★★
Based on 971 reviews
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Product Reviews
★★★★★ 5
Great quality chair, regardless of price.
Color: Black+white, Size: Pack of 1, Color: Black+white, Size: Pack of 1
Great quality chair, regardless of the price, period. So well packaged that it took almost as long to unwrap as assemble. Assembly was easy (loved the Allen wrench with sturdy handle). I am 6'2" and the fit and height adjustments work well for my height. Comfort is personal, so I like the semi-firmness of the seat. While the chair is constructed of heavy gauge plastic the base is solid metal with enamel finish: I love the look. The arm rests line up perfectly to my computer keyboard. I expect many, many years of service.
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Reviewed in the United States on May 17, 2026
★★★★★ 5
Great Value for a Comfortable Home Office Chair
Color: Black, Size: Pack of 1, Color: Black, Size: Pack of 1
I’ve been using this chair for a couple of days now, and honestly, it’s been a solid upgrade from my old one. I work from home most days, so comfort matters a lot—and this chair delivers better than I expected for the price.
The first thing I noticed was the lumbar support. It’s actually adjustable and makes a noticeable difference, especially if you tend to sit for long stretches. My lower back used to get sore after a few hours, but that hasn’t really been an issue since switching to this chair. The mesh back is also a nice touch—it keeps things breathable, which I didn’t think I’d care about until I had it.
Assembly was pretty straightforward. Took me maybe 20–25 minutes without any frustration. Everything lined up well, and the instructions were clear enough.
In terms of comfort, the seat is firm but not hard. It doesn’t feel like one of those super plush chairs, but I actually prefer that because it feels more supportive over time. The reclining feature is smooth, and I like that you can lean back a bit when you need a break.
Overall, I’d say this is a great value for a home office setup. If you want something ergonomic and comfortable without spending a fortune, this chair is definitely worth considering.
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Reviewed in the United States on April 30, 2026
★★★★★ 5
Excellent Office Chair
Color: Black+white, Size: Pack of 1
I just received my TRALT Office Chair. First of all, I was impressed with the packaging of this item. When I opened the box each piece of the chair was wrapped in plastic or bubble wrap. Everything in the box arrived safely and without damage. Secondly, the instructions to assemble the chair were very each to follow. I was impressed with the Allen wrench which had a handle attached to it. This made screwing in the screws very easy. I was able to assemble the chair without any difficulty. Lastly, the look of the chair and the comfort is exceptional. I ordered the black/white chair which looks amazing. The comfort of the chair is really excellent. My back is supported by the lumbar seat and having the armrests being able to go up when not needed is wonderful. The quality of the chair is definitely worth the price.
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Reviewed in the United States on May 9, 2026
★★★★★ 4
a good choice
Color: Black, Size: Pack of 1, Color: Black, Size: Pack of 1
Assembled chair only to find that the lift cylinder was faulty. Would have preferred to be able to just get a replacement cylinder but calling China didn't seem like a viable option. Guessing which one & buying it online would involve paying for a good portion of what the chair cost. Customer service could only offer a replacement or refund. We're disassembling (so much fun?!) to send it back. The chair itself was very comfortable, assembled fairly easily and instructions pretty clear. Again, if we could only have asked the seller for the replacement part......**Update**...Or if the instructions that seemed so clear were clearer!, as we started to disassemble, we decided to see what would happen if the tension knob (see photo) was loosened. IT ALLOWED THE LIFT CYLINDER TO WORK. Not at all what the instructions say. At any rate, we're keeping the chair.
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Reviewed in the United States on June 4, 2026
★★★★★ 5
This chair is amazing
Color: Sky Blue, Size: Pack of 1, Color: Sky Blue, Size: Pack of 1
⭐⭐⭐⭐⭐
Absolutely love this chair! It was super easy to assemble—I had it set up in no time with clear instructions and minimal effort. The comfort level is fantastic; the seat cushion is just right and the back support makes it great for longer sitting sessions.
The color is beautiful in person—clean, modern, and adds a fresh pop to the room without being overwhelming. I also really like the smooth wheels and sturdy build; it feels stable and well-made.
Overall, this is a great combination of style, comfort, and value. Highly recommend!
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Reviewed in the United States on May 4, 2026