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Description
IL-1RAcP/IL-1R3 His Tag Protein, Cynomolgus/Rhesus macaqueProduct Specification Species Cynomolgus Synonyms IL1RAP, IL 1RAcP, C3orf13, IL1R3 Accession P59822 1 Amino Acid Sequence Ser21 Glu359, with C terminal His Expression System HEK293 Molecular Weight 55 65kDa (Reducing) Purity 95% by SDS PAGE & 95% by SEC HPLC Endotoxin <0. 1EU g Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, 5% trehalose, PH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water
Product Specification
| Species | Cynomolgus |
| Synonyms | IL1RAP, IL-1RAcP, C3orf13, IL1R3 |
| Accession | P59822-1 |
| Amino Acid Sequence | Ser21-Glu359, with C-terminal His |
| Expression System | HEK293 |
| Molecular Weight | 55-65kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE & ＞95% by SEC-HPLC |
| Endotoxin | <0.1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, 5% trehalose, PH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1. Eggestøl HØ, Lunde HS, Knutsen TM, Haugland GT. Interleukin-1 Ligands and Receptors in Lumpfish (Cyclopterus lumpus L.): Molecular Characterization, Phylogeny, Gene Expression, and Transcriptome Analyses. Front Immunol. 2020 Apr 2; 11:502. |
Background
Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. Interleukin 1 induces the synthesis of the acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein.
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