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Ships within 48 hours · Estimated delivery Aug 11 - Aug 16
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Description
Renue By Science Trigonelline | High Strength Trigonelline TRG Methylated Niacin - 250mg Trigonilline Supplement Capsules | Non-GMO | Made in The USA & Third-Party TestedRenue By Science Trigonelline TRG Methylated Niacin 250mg supplement capsules. Non GMO. Made in the USA. Third Party Tested. Muscle NAD+ Synthesis: By promoting NAD+ synthesis in muscle through the Preiss Handler pathway, Trigonelline enhances cellular energy and repair, supporting overall health and longevity. Supports muscle NAD+ production, unlike NMN or NR. It provides the precursors needed to generate NAD+ that becomes depleted through cellular
Renue By Science Trigonelline TRG Methylated Niacin 250mg supplement capsules. Non-GMO. Made in the USA. Third-Party Tested.
- Muscle NAD+ Synthesis: By promoting NAD+ synthesis in muscle through the Preiss-Handler pathway, Trigonelline enhances cellular energy and repair, supporting overall health and longevity. Supports muscle NAD+ production, unlike NMN or NR. It provides the precursors needed to generate NAD+ that becomes depleted through cellular metabolism and aging.
- DNA Repair and Cellular Integrity: Encouraging cellular repair and maintaining DNA integrity, Trigonelline protects against cellular damage and promotes health at the molecular level. Additionally donates methyl groups which promote healthy gene expression.
- Protects Against Tissue Aging: Supplies much-needed NAD+ precursors to tissues like the heart, brain, and muscles. NAD+ declines fastest in tissues that experience the most oxidative damage and physiological use, so using Trigonelline to refuel these tissues protects youthful heart, brain, and muscle function, preserving strength and cognition.
- Broad Longevity Support: Unlike other NAD+ precursors, Trigonelline is stable through digestion and enters circulation for systemic tissue delivery. Once in circulation it can support healthy sugar and lipid metabolism and does not cause the flushing effect that many experience with niacin.
- Naturally Occurring NAD+ Support: Trigonelline is found in numerous plant foods including coffee and fenugreek. This highly bioavailable and stable molecule can cross the blood-brain barrier and is quickly metabolized into NAD+, measurably impacting circulating and intracellular levels of this critical molecule.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.3 ★★★★★
Based on 15 reviews
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Product Reviews
★★★★★ 5
Easy to operate.
Color: Black/Battery
Very easy to operate. I was a little confused on how it operated but all I had to do is sit it on top of the can and it operates by itself. When it is done, the lid can be removed or set on top of the can. It doesn't leave any sharp edges. I was using a hand held one but because I have arthritis in my wrist, it is worth the price easy enough for seniors or disabled
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Reviewed in the United States on May 29, 2026
★★★★★ 5
Great, super efficient!
Color: Black/Battery
Love this. Bought it for my mom since she doesn’t have a lot of strength in her hands. Perfect. Kind of slow but gets it done haha.
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Reviewed in the United States on May 10, 2026
★★★★★ 1
Only worked for 1 month.
Color: Black/Battery
This product was delivered on April 20th and worked great. It made a nice clean cut in the metal with no sharp edges and the top of the can lifted up nicely. Yesterday, May 24th, it stopped cutting and unfortunately, the return window closed on May 20th.
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Reviewed in the United States on May 25, 2026
★★★★★ 5
Super safe
Color: Black/Battery
The most easiest and safe can opener to have people with diabetes or heart issues that take blood thinners that can’t get cut this is perfect
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Reviewed in the United States on June 6, 2026
★★★★★ 4
Opens the can weird, but functional
Color: Black/Battery
Ehhh it’s easy to use and gets it open, my only issue is that it doesn’t open a can like a regular can opener where it is cut on top of the can and you can push it in the can to drain if needed. Rather it cuts the outside of the can as it spins around, so it doesn’t fit inside the can. Not very handy when you’re opening a can of tuna and want to drain the tuna juice, so I had to keep my manual one, that I was trying to get rid of by buying this electric one 🙃
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Reviewed in the United States on May 23, 2026