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Description
OTP Recombinant Rabbit mAb (SDT-2002-175)Product Specification Host Rabbit Antigen OTP Synonyms Homeobox protein orthopedia; OTP Immunogen Synthetic Peptide Location Nucleus Accession Q5XKR4 Clone Number SDT 2002 175 Antibody Type Recombinant mAb Isotype IgG Application IHC P Reactivity Hu Predicted Reactivity Ms, Zf Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability &
Product Specification
| Host | Rabbit |
| Antigen | OTP |
| Synonyms | Homeobox protein orthopedia; OTP |
| Immunogen | Synthetic Peptide |
| Location | Nucleus |
| Accession | Q5XKR4 |
| Clone Number | SDT-2002-175 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | IHC-P |
| Reactivity | Hu |
| Predicted Reactivity | Ms, Zf |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:1000 | Hu |
Background
Orthopedia homeobox protein (OTP) is a nuclear transcription factor encoded on chromosome 5q14.1 that belongs to the homeobox family and is indispensable for embryonic neurodevelopment ; in clinical oncology it serves as a highly sensitive and specific immunohistochemical marker that strongly stains typical pulmonary carcinoids while remaining negative in most non-lung well-differentiated neuroendocrine tumors, with negative or weak nuclear OTP expression correlating with worse prognosis in carcinoid patients .
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