SKU: 89607902518

Biotinylated CLEC12A/MICL/CLL-1 Avi&His Tag Protein, Human

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Description

Biotinylated CLEC12A/MICL/CLL-1 Avi&His Tag Protein, HumanProduct Specification Species Human Synonyms CLL1, DCAL2 Accession Q5QGZ9 2 Amino Acid Sequence His65 Ala265, with N terminal His and Avitag Expression System HEK293 Molecular Weight 35 45kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <1EU g Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4. Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid centrifugation. Stability & Storage 12 months

Product Specification


Species Human
Synonyms CLL1, DCAL2
Accession Q5QGZ9-2
Amino Acid Sequence His65-Ala265, with N-terminal His and Avitag
Expression System HEK293
Molecular Weight 35-45kDa (Reducing)
Purity ＞95% by SDS-PAGE
Endotoxin <1EU/μg
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4.
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1. Vitry, J.; Paré, G.; Murru,A.; Charest-Morin, X.; Maaroufi, H.;McLeish, K.R.; Naccache, P.H.;Fernandes, M.J. Regulation of the Expression, Oligomerisation and Signaling of the Inhibitory Receptor CLEC12A by Cysteine Residues in the Stalk Region. Int. J. Mol. Sci. 2021,22, 10207.

Background

Clec12a (also called myeloid inhibitory C-type lectin-like receptor, MICL) was originally described as an ITIM-containing inhibitory CLR expressed by human granulocytes and monocytes. It was suggested that Clec12a recognizes some endogenous ligands as soluble Clec12a could bind to single-cell suspensions isolated from various murine tissues. CLEC12A is a myeloid lineage antigen that is highly expressed by AML cells and LSCs, but not expressed by normal hematopoietic stem cells (HSCs), thus minimizing off-target toxicity.

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Exchange/Return Notes
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SKU: 89607902518

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4.6 ★★★★★
Based on 8 reviews
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Product Reviews
S
Verified Purchase
sandy
Omaha, US
★★★★★ 5
Hollypet Gray is excellent
Color: Gray, Size: 14 IN
This GrayHollpet comes down the assembly line that produces a good product. It is tough and stays together Don't buy the brown one, it started to fall apart in less than 30 days. These can be a good product!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 3, 2026
M
Verified Purchase
Melissa Overton
Lake Worth, US
★★★★★ 4
Super cute
Color: Gray, Size: 8 IN
Super cute in person. Didn’t last two weeks with our aggressive chewer but he sure had fun with it
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Reviewed in the United States on May 6, 2026
B
Verified Purchase
Bob
Draper, US
★★★★★ 5
We call him Armie! Dog loves it.
Color: Blue, Size: 14 IN
The dog loves it! Routinely carries it around squeaking all the way. The squeak is more like a quack and makes everyone giggle. It’s nice and big so a good match for our tall dog. Probably too big though for smaller dogs. Holding up well so far and that’s no mean feat given our pup’s destruction skills.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 28, 2026
T
Verified Purchase
Trust Me!
Belleville, US
★★★★★ 5
The chewability of this toy from 1-10 is a 10 all day 👍🏻
Color: Gray, Size: 8 IN
I have a Boston Terrier and he’s a serious extreme CHEWER! He loves this Hollypet Plush Dog Squeaky Toy Stuffed Armadillo! My doh gnaws on the tail, legs, the ears and the nose and all are still in tact. He’s had it for what I consider a long time. Usually he rips toys apart in the first day but this has been months! I throw this in the washing machine with his other stuffed animal toys simply because the ears, noses and tail get so stiff from chewing on them they need to be washed and they bounce right back just like new. Chewability from 1-10 is a 10 all day long! He plays with it a for a long while each time he uses it. Very active with his Armadillo and it’s so cute and the squeaker is just right, it’s not that loud screaming squeak. If he ever lost this or it got destroyed somehow? I’d buy him this all over again. Worth the money!
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Reviewed in the United States on March 5, 2026
J
Verified Purchase
James Brummett
Omaha, US
★★★★★ 4
Fun dog toy, but not for heavy chewers
Color: Pink, Size: 14 IN
The armadillo is cute. My pittie, Sasha, was very excited to see it. She just had TPLO surgery on her left knee (she tore her ACL just before the 4th of July), and I wanted to get her something she could play with while she convalesces, that isn't a ball—she really likes to run and jump and chase the ball, but with her knee out of commission, I didn't want her to get depressed being trapped in her crate while she heals—with this toy, she was able to keep playing and not over excert herself and get more hurt. It quickly became her favorite toy; she chews it relentlessly and gets made when I take it from her (see below). It makes a funky squeak that's not a high-pitched squeak, like I thought it would be; it's more a low-pitched, lowing sound like a baby calf. One thing I would like to point out to other purchasers about what the description says: "Durable and Long Lasting - Made from premium soft materials, our cute plush dog toys can withstand rough play for indoor or outdoor and last for years to come. The textured surface also helps massage and soothe your dog's gums during playtime" This is a little misleading. It's a good texture and Sasha loved to play with it, but it wasn't very durable. It might be when compared to other chew toys, but not for my baby. She tore the nose off within 20 minutes of getting it. The next morning, she ripped off an ear, and I had to pull the stuffing out of the face so she wouldn't eat it while chewing away. She doesn't seem to mind, but I sure wish it had held up a little more. All-in-all, this was a good toy for a few days.
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Reviewed in the United States on July 29, 2025

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