SKU: 9142894564

APC Rabbit Anti-Mouse NK1.1/CD161 Antibody (S-428-32)

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Description

APC Rabbit Anti-Mouse NK1.1/CD161 Antibody (S-428-32)Product Specification Host Rabbit Antigen NK1. 1 CD161 Synonyms Killer cell lectin like receptor subfamily B member 1C; CD161 antigen like family member C; Lymphocyte antigen 55c (Ly 55c); NKR P1. 9; NKR P1C; Natural killer cell surface protein P1 40 (NKR P1 40); CD161c; Ly55c; Nkrp1c; Klrb1c Immunogen Recombinant Protein Location Membrane Accession P27814 Clone Number S 428 32 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Ms

Product Specification


Host Rabbit
Antigen NK1.1/CD161
Synonyms Killer cell lectin-like receptor subfamily B member 1C; CD161 antigen-like family member C; Lymphocyte antigen 55c (Ly-55c); NKR-P1.9; NKR-P1C; Natural killer cell surface protein P1-40 (NKR-P1 40); CD161c; Ly55c; Nkrp1c; Klrb1c
Immunogen Recombinant Protein
Location Membrane
Accession P27814
Clone Number S-428-32
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse splenocytes
Purification Protein A
Concentration 0.2 mg/ml
Conjugation APC
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 1.25μl per million cells in 100μl volume Ms

Background

NK1.1/CD161, also known as KLRB1, is a receptor protein expressed on the surface of natural killer (NK) cells and certain T cells. In mice, NK1.1 belongs to the NKRP1 receptor family and interacts with C-type lectin-related molecules, playing a role in immune recognition and regulation. In humans, CD161 on NK cells interacts with ligands such as LLT1, and this interaction is inhibitory, helping to regulate NK cell function. Additionally, CD161 is involved in intracellular signaling pathways, such as the AKT pathway, which influences NK cell activity. This protein is also a marker for different subsets of NK cells, with high expression in certain mature and cytotoxic NK cell populations.

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SKU: 9142894564

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