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Due to some magical mayhem, the Transformers find themselves in Equestria, and the Decepticons have teamed up with nefarious Pony Villains, which can't lead to anything good.
In My Little Pony: Adventures in Equestria Deck-Building Game – Collision Course Expansion, the Mane Six (and Spike!) team up with the Autobots as two-in-one character cards. Use the Autobots abilities by generating Energon on cards — or getting an energy boost by eating a Sugar Cube instead.