SKU: 26887216666

Pterostilbene Pro 250 - 250 mg, 60 capsules

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Description

Pterostilbene Pro 250 - 250 mg, 60 capsulesPterostilbene is a powerful antioxidant that is similar to, but more bioavailable than resveratrol. Pterostilbene promotes longevity and improves markers associated with heart and brain health. Supports cardiovascular health* Promotes brain cell health* Activates sirtuins to support healthy aging Boosts effectiveness of NMN View Certificate of Analysis Research Supported Benefits: Supports Longevity. Pterostilbene activates longevity genes known as

Pterostilbene is a powerful antioxidant that is similar to, but more bioavailable than resveratrol. Pterostilbene promotes longevity and improves markers associated with heart and brain health.

  • Supports cardiovascular health* 
  • Promotes brain cell health* 
  • Activates sirtuins to support healthy aging 
  • Boosts effectiveness of NMN 

View Certificate of Analysis

Research-Supported Benefits:

Supports Longevity. Pterostilbene activates “longevity genes” known as sirtuins. Research shows that activating sirtuins promotes cellular health and extends lifespan of animals. 1 2 Activating sirtuins aids in DNA repair, promoting cellular stress resistance, regulating autophagy (cellular detoxification) and inflammation. 3

Promotes Heart Health. Research shows that pterostilbene promotes heart health in a variety of ways, one of which is reducing oxidative stress of the heart. 4 Oxidative stress contributes to inflammation and accelerated aging of heart cells. Reducing levels of oxidative stress reduces risk of age-related decline of heart health.

Protects the Aging Brain. Pterostilbene has been shown to reduce neuroinflammation (inflammation of brain cells), reducing oxidative-stress-related damage to brain cells 5. Research shows that neuroinflammation contributes to age-related brain decline symptoms such related to memory and information processing.6

References:

1. Cheng Y, Di S, Fan C, et al. SIRT1 activation by pterostilbene attenuates the skeletal muscle oxidative stress injury and mitochondrial dysfunction induced by ischemia reperfusion injury. Apoptosis. 2016;21(8):905-916. doi:10.1007/s10495-016-1258-x 

2. Lee SH, Lee JH, Lee HY, Min KJ. Sirtuin signaling in cellular senescence and aging. BMB Rep. 2019;52(1):24-34. doi:10.5483/BMBRep.2019.52.1.290 doi:10.5483/BMBRep.2019.52.1.290 

3. Vazquez BN, Thackray JK, Serrano L. Sirtuins and DNA damage repair: SIRT7 comes to play. Nucleus. 2017;8(2):107-115. doi:10.1080/19491034.2016.1264552

4. Kosuru R, Kandula V, Rai U, Prakash S, Xia Z, Singh S. Pterostilbene Decreases Cardiac Oxidative Stress and Inflammation via Activation of AMPK/Nrf2/HO-1 Pathway in Fructose-Fed Diabetic Rats. Cardiovasc Drugs Ther. 2018;32(2):147-163. doi:10.1007/s10557-018-6780-3

5. Park B, Lee YJ. Pterostilbene Improves Stress-Related Behaviors and Partially Reverses Underlying Neuroinflammatory and Hormonal Changes in Stress-Challenged Mice. J Med Food. 2021;24(3):299-309. doi:10.1089/jmf.2020.4766

6. Ahmad MA, Kareem O, Khushtar M, et al. Neuroinflammation: A Potential Risk for Dementia. Int J Mol Sci. 2022;23(2):616. Published 2022 Jan 6. doi:10.3390/ijms23020616

  • Pterostilbene has been shown to activate longevity genes known as sirtuins, which play a critical role in regulating cellular aging. 
  • Sirtuins require NAD+ for fuel, making pterostilbene and NMN a perfect supplement combination to promote longevity. 
  • By activating sirtuins, pterostilbene supports DNA stability and promotes DNA repair. 
  • Pterostilbene’s antioxidant effects promote heart and brain health by reducing oxidative stress and inflammation. 
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving %DV
Pterostilbene 250 mg
† Daily Value (DV) not established.
REV.08.25 

  • OTHER INGREDIENTS: Hypromellose (capsule), rice flour.
  • SUGGESTED DAILY USE: Take one (1) capsule 1-2 times per day, preferably with food.
  • CAUTION: For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF  CHILDREN. Store in a cool and dry place aer opening.

Clinical-Supported Dosing. ProHealth Longevity’s Pterostilbene Pro 250 contains 250 mg of pterostilbene per serving, a clinically effective dose to promote longevity.

Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.

Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.

Shipping Notes
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Exchange/Return Notes
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  • To process your return/exchange, please contact us at [email protected]
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SKU: 26887216666

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4.2 ★★★★★
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LJ
West Palm Beach, US
★★★★★ 5
Excellent quality chews. Tiny Puppy size is perfect for adult toy breed dogs.
Flavor Name: REAL Bacon, Size: Puppy (2-Pack)
I bought the Tiny Puppy Bacon flavor 2-pack package of these, and my dog and his sister are obsessed with them. They chew on them multiple times every day. They seem to be fairly durable, although I expect they will break down over time, which is okay as it’s a chew. I like that they stay intact, with no chunks breaking off for the dogs to swallow. The dogs do ingest a small amount as the material breaks down, but I always supervise them when they have these, and there haven’t been any problems. It’s difficult to find good chews for toy breed dogs like our 12-pound Shih Tzus, so I was happy to find these. They are pricey, but I believe they are worth it. The dogs love to carry them around, and my little guy even plays with his chew sometimes like it’s a toy.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 20, 2026
M
Verified Purchase
Marie Phillips
Chelsea, US
★★★★★ 5
Durable, engaging, and dog approved
Flavor Name: REAL Bacon/REAL Maplewood, Size: Puppy Tiny (2-Pack)
These chew toys are great for keeping dogs entertained and engaged, especially for gentle chewers. The quality feels strong and they hold up well compared to many other toys. The real bacon scent keeps dogs interested and coming back to them often. I’ve ordered multiple packs over time for my own dogs and even gifted them to others because they’re so well liked.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 2, 2026
G
Verified Purchase
GamsGal
Carnegie, US
★★★★★ 4
The "Y" is a staple! The other is useless.
Flavor Name: REAL Bacon, Size: Small – 2 Pack
Leaving a 4-star review because she has chewed this "Y-shaped" Benebone almost down to the nubbins. At first she didn't want much to do with it, but something clicked and once she started chewing it, it's become a staple in her chewing repertoire. But the other shape... the double-pull with the lines on it... is apparently not chewable for her. She'll tote it around, but won't really sink her teeth into that one. She's still a puppy, so maybe she'll start on the double-pull shaped one later. But we'll probably hafta get a larger Y-shape in a month or two... that one's totally worth it!
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Reviewed in the United States on February 26, 2026
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Verified Purchase
Personal info
Pawtucket, US
★★★★★ 5
My dog lives these. Great for the puppy chewing stage.
Flavor Name: REAL Bacon/REAL Maplewood, Size: Puppy Tiny (2-Pack)
My dog loves these bones. I love them too because I dont have to worry about him choking in them or biting off small.peices. Great for puppies going through the chewing stage. My dog seeks these bones out over other toys. The size is great perfect for medium sized dog. Material is durable and lasting. Occupy my dog for a long time.
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Reviewed in the United States on May 27, 2026
C
Verified Purchase
Chennell Brewer
Omaha, US
★★★★★ 5
Dog approved!
Flavor Name: REAL Bacon, Size: Puppy (2-Pack)
Our American Eskimo loves these! She chews on them often and they have lasted . I would buy them again.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 10, 2026

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