SKU: 62233332691

CD105 Mouse mAb (S-837-10)

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Description

CD105 Mouse mAb (S-837-10)Product Specification Host Mouse Synonyms Endoglin, ENG, END Immunogen Recombinant Protein Location Cell membrane Accession P17813 Clone Number S 837 10 Antibody Type Mouse mAb Isotype IgG2b,k Application FCM Reactivity Hu Purification Protein A Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of receipt reconstitution, 20

Product Specification


Host Mouse
Synonyms Endoglin, ENG, END
Immunogen Recombinant Protein
Location Cell membrane
Accession P17813
Clone Number S-837-10
Antibody Type Mouse mAb
Isotype IgG2b,k
Application FCM
Reactivity Hu
Purification Protein A
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
FCM 1:2000 null

Background

Endoglin (ENG) is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex. It is also commonly referred to as CD105, END, FLJ41744, HHT1, ORW and ORW1. Endoglin has been found to be an auxiliary receptor for the TGF-beta receptor complex. It thus is involved in modulating a response to the binding of TGF-beta1, TGF-beta3, activin-A, BMP-2, BMP-7 and BMP-9. Beside TGF-beta signaling endoglin may have other functions. It has been postulated that endoglin is involved in the cytoskeletal organization affecting cell morphology and migration. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. In humans endoglin may be involved in the autosomal dominant disorder known as hereditary hemorrhagic telangiectasia (HHT) type 1.

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SKU: 62233332691

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4.1 ★★★★★
Based on 7 reviews
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Product Reviews
A
Verified Purchase
Amazon Customer
Fort Morgan, US
★★★★★ 3
Water Pic is Awesome
I love both the water pick and the toothbrush. The battery life on both items is really good. the only thing that should be included but isnt, is a cap to cover the mouth pieces when not in use. Unfortunately while I have had no problem recharging the water pick, the toothbrush will not recharge and I been unable to use it since the battery died. Can someone from the company contact to replace the toothbrush. Thank you
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Reviewed in the United States on December 6, 2022
M
Verified Purchase
Melody
San Leandro, US
★★★★★ 5
Great Product
Use the toothbrush and pik in the shower! They work great - I am very satisfied with these products!
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Reviewed in the United States on January 16, 2023
T
Verified Purchase
TD Maclin
Fort Morgan, US
★★★★★ 1
Poor not functional upon arrival
Does not include necessary parts to operate the device. Wall charger not included. Very poor.
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Reviewed in the United States on November 14, 2022
H
Hunter Warrior
Bozeman, US
★★★★★ 5
Very nice water flosser & sonic toothbrush set
This is a very nice set of a portable water flosser and a basic sonic toothbrush. They are sturdy and appear to be well made. They are relatively compact and easy to pack to travel. They work well and do a pretty decent job of flossing and cleaning my teeth and gum, leaving my mouth feeling fresh and clean. The water flosser is a one-piece design with a detachable water tank. It isn't overly bulky but rather comfortable to hold. It comes with 4 interchangeable nozzle tips (2 standard, 1 orthodontic & 1 tongue cleaner). It has 4 cleaning modes including a custom mode in which you can manually adjust the water jet pressure (10 intensity levels). It is pretty easy to use and does a decent job of removing food particles from between the teeth and along the gum line. Charging is done via a special USB cable (provided). The sonic toothbrush is basic and functional. It brushes well and leaves my teeth feeling fresh and clean. It has the usual 2-minute timer and 30-second interval reminder. The 3 basic cleaning modes are adequate for my needs. It comes with 4 replacement brush heads, which is essentially a 1-year supply. It is rechargeable via USB-C (charging cable provided). All in all, I'm pretty pleased with this water flosser and sonic toothbrush. They work well for what they are designed to do. Comfortable to hold and easy to use. The material and build quality seems decent as well. I think it is a good investment for everyday dental care. They get the job done.
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Reviewed in the United States on May 21, 2022
A
Astrid
Natrona Heights, US
★★★★★ 5
Perfect For Those Upgrading From Manual Cleansing
Whether you just need to replace your old electric systems or you are moving on up to the electric age, this is a good set to go with. Also makes for a nice gift. You get both a sonic toothbrush and an oral flosser. Once you take that step, you'll never go back. So much more thorough cleansing all around. The toothbrush is nice and powerful at 40,000 VPM. That's pretty powerful and gives you a much deeper cleansing. Personally, I wouldn't go any lower than that unless you have really sensitive gums. Of course, you can adjust intensities with this, so you'll be fine either way. The oral flosser is good and will get what your toothbrush misses. That's not a reflection on this particular toothbrush, but on toothbrushes of any kind as a whole. Does a great job at removing all sorts of stuff lodged between your teeth. Easy to use and you won't have a water line getting in your way. I would highly suggest that you pour a little bit of mouthwash in with your flosser for an even more effective cleansing. You get several replacement heads for your toothbrush and several different tips for the flosser. Enough that you'll have a very clean mouth for a good, long time.
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Reviewed in the United States on June 1, 2022

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