SKU: 21703888263

Alexa Fluor 647-Labeled CD20 Flag&His Tag Full Length Protein, Human (Detergent)

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Description

Alexa Fluor 647-Labeled CD20 Flag&His Tag Full Length Protein, Human (Detergent)Product Specification Species Human Synonyms B lymphocyte surface antigen B1MS4A1B lymphocyte antigen CD20Membrane Spanning 4 Domains A1Leukocyte Surface Antigen Leu 16CD20 AntigenCD20Bp35Membrane Spanning 4 Domains Subfamily A Member 1CD20 ReceptorLEU 16CVID5MS4A2B1S7Antigens CD20Membrane Spanning 4 Domains Subfamily A Member 1B Lymphocyte Cell Surface Antigen B1 Accession P11836 Amino Acid Sequence Full length, with Flag tag at N Terminus, and His

Product Specification


Species Human
Synonyms B-lymphocyte surface antigen B1,MS4A1,B-lymphocyte antigen CD20,Membrane Spanning 4-Domains A1,Leukocyte Surface Antigen Leu-16,CD20 Antigen,CD20,Bp35,Membrane-Spanning 4-Domains Subfamily A Member 1,CD20 Receptor,LEU-16,CVID5,MS4A2,B1,S7,Antigens, CD20,Membrane-Spanning 4-Domains, Subfamily A, Member 1,B-Lymphocyte Cell-Surface Antigen B1
Accession P11836
Amino Acid Sequence

Full length, with Flag tag at N-Terminus, and His tag at C-Terminus

Expression System HEK293
Molecular Weight

35.4 kDa

Conjugation Alexa Fluor® 647
Tag His Tag, Flag Tag
Physical Appearance Liquid
Storage Buffer

25mM Hepes,150mM NaCl,0.02%DDM

Stability & Storage

· 16 months from date of receipt stored at -80℃.
· 1 week,2 to 8℃ under sterile conditions.
· Recommend to aliquot the protein into smaller quantities for optimal storage.
· Please avoid repeated freeze-thaw cycles.

Reference

1. Rougé L, Chiang N, Steffek M, et al. Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab[J]. Science, 2020, 367(6483): 1224-1230.

Background

CD20 is a 33-37 kDa non-glycosylated protein present on the surface of normal and malignant B lymphocytes and is a member of the MS4A (membrane-spanning 4-domain family A) protein family. The CD20 protein comprises four hydrophobic transmembrane domains, one intracellular domain, and two extracellular domains (a large loop and a small loop), with both the N- and C-termini located within the cytosol. CD20 is associated with several key molecules, including the major histocompatibility complex class II (MHCII), CD40 molecule, B-cell receptor (BCR), and the C-terminal src kinase-binding protein (CBP). CBP interacts with Src kinases such as LYN, FYN, and LCK.A deficiency in CD20 has been shown to result in a reduced number of circulating memory B cells, decreased isotype switching of immunoglobulins (Ig), and lower IgG antibody levels. It is also linked to various pathophysiological diseases and disorders.CD20 plays a crucial role in multiple physiological processes and is thus a promising therapeutic target. The CD20 protein product has the potential to enhance drug discovery efforts in related fields.
Shipping Notes
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Exchange/Return Notes
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SKU: 21703888263

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4.9 ★★★★★
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Quona
Lowell, US
★★★★★ 5
Great product!
Love this product. Lightweight and feels great on the skin.
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Reviewed in the United States on June 7, 2026
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Jennifer Donnelly
Louisville, US
★★★★★ 5
Pleasantly surprised
I’m two jars in and love it. I do use Botox, retinol, a good face wash, wash moisturize twice daily, etc etc. I struggle with moisturizer because I’m prone to breakouts. Idk what it is about this one but my skin loves it. It feels refreshed and soft. Added bonus, my eyebrows and lashes have gotten longer and darker quick! Obviously we all respond differently to products but I’ll be keeping this in my rotation
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Reviewed in the United States on June 3, 2026
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Deb from the Ridge
Cuba, US
★★★★★ 5
A thick and rich cream that smooths on nicely!
So I jumped on the Korean skincare bandwagon and decided to purchase some of the DR MELAXIN Products to try! I read many good reviews and decided it was worth the money. This first product is the Dr Melaxin Calcium cemenrete calcium volume cream. It comes in a 1.76 ounce glass jar. On the label there is a lot of word descriptions so I will add a few: Ex volume firming, rebornic 10,000 ppm hydrolyzed elastin and collagen extract. I have photographed label for viewing. The directions indicate to "apply a small amount of cream onto your face especially around the under-eye area". I found the cream thick and rich and I used it in addition to another Dr Melaxin neck and face product so I concentrated on only neck and under eye area. It is neutral in scent and is very thick so it feels like it is absorbing nicely. I have been using it for about a month now and have definitely noticed some improvement in the neck area so i will continue to use and layer with other products. I do recommend this line as the ingredients seem effective so far!
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Reviewed in the United States on June 4, 2026
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E.R.
Belleville, US
★★★★★ 5
Good product for face.
Great product. Works well with decreasing lines in face after half is used and with the serum. It does leave somewhat of a sticky (not grimy) texture which is uncomfortable if using at night.
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Reviewed in the United States on June 1, 2026
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E. L. Phipps
Lexington, US
★★★★★ 4
Loose under eye skin tightened and brightened!
I love this cream! It makes a huge difference in the strength of the skin under my eyes and smooths the look and feel of the wrinkled skin under my eyes. It brightens my under eye circles. I gave 4 stars because if you use too much it will start to roll off almost like skin does when it sheds or when you exfoliate. I use less now and it’s perfect.
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Reviewed in the United States on May 3, 2026

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