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Description
MCL1 Recombinant Rabbit mAb (S-2640-208)Product Specification Host Rabbit Antigen MCL1 Synonyms Induced myeloid leukemia cell differentiation protein Mcl 1 homolog; Bcl 2 related protein EAT mcl1; Mcl1 Immunogen Synthetic Peptide Location Cytoplasm, Nucleus, Mitochondrion Accession P97287 Clone Number S 2640 208 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Ms, Rt Positive Sample L 929, A20, C2C12, rat kidney, rat stomach Purification Protein A Concentration 0. 5 mg ml
Product Specification
| Host | Rabbit |
| Antigen | MCL1 |
| Synonyms | Induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Bcl-2-related protein EAT/mcl1; Mcl1 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus, Mitochondrion |
| Accession | P97287 |
| Clone Number | S-2640-208 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Ms, Rt |
| Positive Sample | L-929, A20, C2C12, rat kidney, rat stomach |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Ms, Rt |
Background
MCL1 (Myeloid cell leukemia 1) is an anti-apoptotic member of the BCL-2 protein family that plays a crucial role in regulating cell survival and death by binding to and neutralizing pro-apoptotic proteins such as BAK and BIM, thereby preventing mitochondrial outer membrane permeabilization and subsequent activation of the intrinsic apoptotic pathway.
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Exchange/Return Notes
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