SKU: 32031597489

DNA Ligase IV/LIG4 Recombinant Rabbit mAb (S-2237-64)

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Description

DNA Ligase IV/LIG4 Recombinant Rabbit mAb (S-2237-64)Product Specification Host Rabbit Antigen DNA Ligase IV LIG4 Synonyms DNA ligase 4; DNA ligase IV; Polydeoxyribonucleotide synthase [ATP] 4 Immunogen Recombinant Protein Location Nucleus Accession P49917 Clone Number S 2237 64 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Rt Positive Sample PC 12, rat testis Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer

Product Specification


Host Rabbit
Antigen DNA Ligase IV/LIG4
Synonyms DNA ligase 4; DNA ligase IV; Polydeoxyribonucleotide synthase [ATP] 4
Immunogen Recombinant Protein
Location Nucleus
Accession P49917
Clone Number S-2237-64
Antibody Type Recombinant mAb
Isotype IgG
Application WB, IHC-P
Reactivity Rt
Positive Sample PC-12, rat testis
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Rt
IHC-P 1:200 Rt

Background

DNA Ligase IV, also known as LIG4, is a crucial enzyme involved in the non-homologous end joining (NHEJ) pathway, which is essential for repairing DNA double-strand breaks. It plays a vital role in maintaining genomic stability by facilitating the ligation of broken DNA ends. LIG4 forms a complex with other proteins such as XRCC4 and XLF, enhancing its stability and activity. This enzyme is particularly important in the repair of DNA damage caused by ionizing radiation and certain chemotherapeutic agents. Mutations or deficiencies in LIG4 can lead to severe immunodeficiency and developmental disorders due to impaired V(D)J recombination, a process critical for the generation of antigen receptor diversity in the immune system.

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SKU: 32031597489

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Manmomma
Lake Worth, US
★★★★★ 2
No squeak balls
Color: A.Green+Orange
They don’t squeak. They bounce much either.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 25, 2026
O
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Odalis Perez
Charlottesville, US
★★★★★ 3
Too big for puppies
Color: A.Green+Orange
The balls were a bit too big for my 6 month chihuahuas:/ they are as big as a tennis ball so puppies didn’t like nor play with them
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Reviewed in the United States on April 26, 2026
S
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Shawn
Lowell, US
★★★★★ 5
Frenchie approved
Color: A.Orange+Blue+Green
Frenchie approved
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Reviewed in the United States on May 6, 2026
K
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Karen W.
Lowell, US
★★★★★ 5
Soft and light
Color: A.Orange+Blue+Green
My doxie loves them
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Reviewed in the United States on April 26, 2026
A
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Amanda Dutton
Pawtucket, US
★★★★★ 5
Great toy
Color: Pawty
My dog loves this toy. I was pleasantly surprised to see it was a decent size for a stuffed toy, and not tiny. It seems pretty sturdy as my dog can shred some stuffed toys, but this one is still standing with the squeaker intact. The rope is securely attached within the toy and my dog likes to play some tug-of-war with it. Would recommend to other pet parents.
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Reviewed in the United States on March 27, 2026

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