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Description
Non-muscle Myosin IIB/MYH10 Recombinant Rabbit mAb (S-299-3)Product Specification Host Rabbit Antigen Non muscle Myosin IIB MYH10 Synonyms Myosin 10, Cellular myosin heavy chain, type B, Myosin heavy chain 10, Myosin heavy chain, non muscle IIb, NMMHC B, NMMHC II b; NMMHC IIB, NM IIB Immunogen Synthetic Peptide Accession P35580 Clone Number S 299 3 Antibody Type Recombinant mAb Application WB, IHC P Reactivity Hu, Ms, Rt Predicted Reactivity Rb Purification Protein A Concentration 0. 1 mg ml Conjugation
Product Specification
| Host | Rabbit |
| Antigen | Non-muscle Myosin IIB/MYH10 |
| Synonyms | Myosin-10, Cellular myosin heavy chain, type B, Myosin heavy chain 10, Myosin heavy chain, non-muscle IIb, NMMHC-B, NMMHC II-b; NMMHC-IIB, NM-IIB |
| Immunogen | Synthetic Peptide |
| Accession | P35580 |
| Clone Number | S-299-3 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P |
| Reactivity | Hu, Ms, Rt |
| Predicted Reactivity | Rb |
| Purification | Protein A |
| Concentration | 0.1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:4000 | |
| IHC | 1:100 |
Background
Myosin-10 also known as myosin heavy chain 10 or non-muscle myosin IIB (NM-IIB) is a protein that in humans is encoded by the MYH10 gene. Non-muscle myosins are expressed in a wide variety of tissues, but NM-IIB is the only non-muscle myosin II isoform expressed in cardiac muscle, where it localizes to adherens junctions within intercalated discs. NM-IIB is essential for normal development of cardiac muscle and for integrity of intercalated discs. Mutations in MYH10 have been identified in patients with left atrial enlargement.
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