SKU: 59863304929

Mouse Anti-Human TCR α/β Antibody (S-R686)

Sale price$90.00 Regular price$100.00
Save 10%

Pay in installments of $25.00 with ShopPay, AfterPay and Klarna

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Aug 17 - Aug 22

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

Mouse Anti-Human TCR α/β Antibody (S-R686)Product Specification Host Mouse Antigen TCR Synonyms TCR; TCR Location Cell membrane Accession P01848 P01850 Clone Number S R686 Antibody Type Mouse mAb Application FCM Reactivity Hu Positive Sample Human PBMC Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4 Stability & Storage 12 months from date of receipt reconstitution, 2 to 8 C as supplied. Dilution application dilution species FCM 1: 200 Hu

Product Specification


Host Mouse
Antigen TCR α/β
Synonyms α/β TCR; TCR α/β
Location Cell membrane
Accession P01848、 P01850
Clone Number S-R686
Antibody Type Mouse mAb
Application FCM
Reactivity Hu
Positive Sample Human PBMC
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 1:200 Hu

Background

The T cell receptor (TCR) α and β proteins are essential components of the αβ T cell receptor, a heterodimeric surface protein expressed on T lymphocytes that recognizes antigenic peptides presented by major histocompatibility complex (MHC) molecules. The TCR α chain is encoded by the TRAC (T cell receptor alpha constant) and TRAV (T cell receptor alpha variable) genes, while the TCR β chain is encoded by the TRBC (T cell receptor beta constant) and TRBV (T cell receptor beta variable) genes, along with diversity (TRBD) and joining (TRBJ) segments, enabling extensive combinatorial diversity. Structurally, both chains consist of a variable (V) domain responsible for antigen recognition and a constant (C) domain that anchors the receptor to the cell membrane. The TCR αβ heterodimer associates with the CD3 complex (CD3γε, CD3δε, and CD247 ζζ) to form a functional TCR-CD3 signaling unit, which transmits activation signals upon peptide-MHC engagement. TCR β undergoes V(D)J recombination during thymic development, contributing to the receptor's antigen specificity, whereas TCR α lacks a D segment but still undergoes recombination for diversity. Mutations or dysregulation in TCR α/β genes can lead to immune disorders, including T cell malignancies and autoimmune diseases. TCR αβ T cells are critical for adaptive immunity, mediating responses against infections, tumors, and self-antigens in autoimmune conditions.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 59863304929

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.3 ★★★★★
Based on 6 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
K
Verified Purchase
KFF
Boise, US
★★★★★ 5
Great little rug!
Color: Ivory White, Size: 2' x 3' (Sheepskin Shape), Color: Ivory White, Size: 2' x 3' (Sheepskin Shape)
This nice little sheepskin rug is the perfect finishing touch to my little reading nook. It’s soft and thick. Follow the enclosed instructions to fluff it up. I was going to order a second one but saw that the price jumped nearly $10 in a week. It’s nice but it’s not worth that amount. I’d buy it on sale though. Five stars.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 6, 2026
W
Verified Purchase
Waldemar G.
Lexington, US
★★★★★ 5
Feels good under feet.
Size: 2'2" x 3'3" (Oblong), Size: 2'2" x 3'3" (Oblong)
I have full bed (see picture). It’s sheepskin rug from single pelt. Bigger maybe would be maybe nicer but there would have to be genetically modified sheep for bigger pelt or sheepskin from 2 pelts. Price is fair in my opinion. Feels amazing to wake up and put feet on it. Appearance is nice just look at picture. I had fake rug in the past and feeling between this and the previous one is day and night. I like it and I love it. Just measure your area before purchasing this product and you should be ok.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 31, 2026
U
Verified Purchase
un
Belleville, US
★★★★★ 5
Best quality for the best price I've found
Size: 2' x 3' (Oblong)
As a lover of sheepskin everything, I will say this is one of the best pelts I've bought. Very thick n fluffy, very soft, clean, and no smell...and the best price I've found as well. I'm buying more of these!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 9, 2025
J
Verified Purchase
jade s.
Louisville, US
★★★★★ 5
Good quality
Size: 2' x 3' (Oblong), Size: 2' x 3' (Oblong)
Fluffed up super nicely same night upon opening. Very soft and thick fur. My dog utterly loves it!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 16, 2026
H
Verified Purchase
Horse 🐎 Girl
Houston, US
★★★★★ 5
It’s so soft and beautiful
Size: 2' x 3' (Oblong)
It’s very soft and cozy for the cats
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 14, 2026

recommand products