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Description
PIK3CD Recombinant Rabbit mAb (SDT-1978-148)Product Specification Host Rabbit Antigen PIK3CD Synonyms Phosphatidylinositol 4,5 bisphosphate 3 kinase catalytic subunit delta isoform; PI3 kinase subunit delta; PI3K delta; PI3Kdelta; PtdIns 3 kinase subunit delta; Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit delta (PtdIns 3 kinase subunit p110 delta; p110delta) Immunogen Synthetic Peptide Location Cytoplasm Accession O00329 Clone Number SDT 1978 148 Antibody Type
Product Specification
| Host | Rabbit |
| Antigen | PIK3CD |
| Synonyms | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; PI3-kinase subunit delta; PI3K-delta; PI3Kdelta; PtdIns-3-kinase subunit delta; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta (PtdIns-3-kinase subunit p110-delta; p110delta) |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm |
| Accession | O00329 |
| Clone Number | SDT-1978-148 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu, Ms |
| Positive Sample | Jurkat, K562, HT-1080, moues spleen, mouse brain |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms |
| IHC-P | 1:250 | Hu, Ms |
| ICC | 1:500 | Hu |
Background
PIK3CD is a gene that encodes a protein which is an integral part of the phosphatidylinositol 3-kinase (PI3K) signaling pathway. This pathway is crucial for various cellular functions including cell growth, proliferation, survival, and metabolism. The PIK3CD protein specifically refers to the delta isoform of the catalytic subunit of PI3K. It is predominantly expressed in immune cells and plays a significant role in the regulation of immune responses. Abnormal activation or mutations in the PIK3CD gene can lead to a range of diseases including certain types of leukemia and other immune-related disorders. Understanding its function and regulation is important for developing targeted therapies in cancer and immune system disorders.
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